A Computational Framework for Planning Therapeutical Sessions aimed to Support the Prevention and Treatment of Mental Health Disorders using Emotional Virtual Agents

[EN] Interaction is defined as the realization of a reciprocal action between two or more people or things. Particularly in computer science, the term interaction refers to the discipline that studies the exchange of information between people and computers, and is generally known by the term Human-Computer Interaction (HCI). Good design decisions and an adequate development of the software is required for efficient HCI to facilitate the acceptability of computer-based applications by the users. In clinical settings it is essential to eliminate any barrier and facilitate the interaction between patients and the system. A smooth communication between the user and the computer-based application is fundamental to maximise the advantages and functionalities offered by the system. The design of these applications must consider the personal and current needs of the user by applying a User-Centered Design methodology. The main purpose of this research work is to contribute in the improvement of HCI-based applications addressed to the clinical context, particularly to enhance computer-based interactive sessions to support people suffering from a mental disorder such as Major Depression (MD). Thanks to the advances in Artificial Intelligence techniques, it is now possible to partially automate complex tasks such as the continuous provision of Cognitive-Behavioural Therapies (CBTs) to patients. These CBTs require good levels of adaptability and variability during the interaction with the patient that facilitates the acceptability in the user, an optimal usability and good level of engagement for a successful mid/long term use of the application and treatment adherence. The modelling of complex deliberative and affective processes in artificial systems can be applied to support the prevention and treatment of mental health related issues, enhancing the continuous and remote assistance of patients, saving some economical and clinical resources and reducing the waiting lists in the health services. In this regard, the efforts of this Thesis have been concentrated on the research of two main lines: (1) the generation and planning of adequate contents in an interactive system to support the prevention and treatment of MD based on characteristics of the user; and (2) the modelling of relevant affective processes able to communicate the contents in an emotional effective way taking into account the importance of the affective conditions associated with the MD in the users. Rule Based Systems and the appraisal theory of emotions have been the roots used to develop the main two modules of the computational Framework presented: the Contents Management and the Emotional Modules. Finally, the obtained Framework was integrated into two interactive systems to evaluate the achievement of the research objectives. The first system has been developed in the context of the Help4Mood European research project and its main aim was to support the remote treatment of patients with MD. The second scenario was a system developed to prevent MD and suicidal thoughts in the University community, which was developed in the context of the local PrevenDep research project. These evaluations have indicated that the proposed Framework has reached good levels of usability and acceptability in the target users thanks to the personalizations and adaptation capabilities of the contents and in the way how these contents are communicated to the user. The research work and the obtained results in this Thesis has contributed to the state of the art in HCI-based systems used as support in therapeutic interventions for the prevention and treatment of MD. This was obtained by the combination of a personalized content management to the patient, and the management of the affective processes associated to these pathologies. The developed work also identifies some research lines that need to be addressed in future works to get better HCI systems used for therapeutic purposes.[ES] Interactuar se define como la realización de una acción recíproca entre dos o más personas o cosas. Particularmente en informática, el término interacción se refiere a la disciplina que estudia el intercambio de información entre las personas y computadoras, y suele conocerse por el término anglosajón Human-Computer Interaction (HCI). Un buen diseño y un adecuado desarrollo del software es necesario para lograr una HCI eficiente que facilite la aceptabilidad del sistema por el usuario. En entornos clínicos es fundamental eliminar cualquier tipo de barrera y facilitar la interacción entre los pacientes y el computador. Es de vital importancia que haya una buena comunicación entre usuario y computador, por este motivo el sistema debe de estar diseñado pensando en las necesidades actuales, cambiantes y personales del usuario, basándose en la metodología de diseño centrado en el usuario. El propósito principal de esta investigación es la identificación de mejoras en HCI aplicada en entornos clínicos, en concreto para dar soporte a personas con trastornos mentales como la Depresión Mayor (DM) y que precisan de terapias psicológicas adecuadas y continuas. Gracias a técnicas de Inteligencia Artificial, es posible automatizar eficientemente ciertas acciones asociadas a los procesos de las terapias cognitivo-conductuales (CBTs, del inglés Cognitive-Behavioural Therapies). Los sistemas de ayuda a la CBT, requieren de una adaptabilidad y variabilidad en la interacción para favorecer la usabilidad del sistema y asegurar la continuidad de la motivación del paciente. Una buena gestión de esta automatización influiría en la aceptabilidad de los pacientes y podría mejorar su adherencia a los tratamientos y por consiguiente mejorar su estado de salud. Adicionalmente, la unión de procesos deliberativos dinámicos pueden liberar recursos clínicos, mejorando el control de los pacientes, y reduciendo los tiempos de espera y los costes económicos. En este sentido, los esfuerzos de esta Tesis se han centrado en la investigación de dos líneas diferentes: (1) la selección y planificación adecuada de los contenidos presentados durante la interacción a través de una planificación dinámica y personalizada, y (2) la adecuación de la comunicación de los contenidos hacia el paciente tomando en cuenta la importancia de los procesos afectivos asociados a estas patologías. Los Sistemas Basados en Reglas (SBR) han sido la herramienta utilizada para dar soporte a los dos módulos principales que componen el Framework presentado en esta Tesis: el módulo de gestión de los contenidos y el módulo emocional. Concluida la fase de diseño, desarrollo y testeo, el Framework fue adaptado e integrado en sistemas reales, para validar la viabilidad y la adecuación del marco de trabajo de esta Tesis. En primer lugar, el sistema se aplicó durante tres años en el tratamiento de la DM en varios centros clínicos europeos en el contexto del Proyecto Europeo de investigación Help4Mood. Finalmente, el sistema fue evaluado en la tarea de prevención de la DM y del suicidio en el Proyecto Local de investigación PrevenDep, de un año de duración. El feedback de estas evaluaciones demostraron que el HCI del Framework tiene unos niveles altos de usabilidad y aceptación, gracias a la personalización, variabilidad y adaptación de los contenidos y de la comunicación de los mismos. Los experimentos computacionales llevados a cabo en esta Tesis han permitido avanzar el estado del arte de sistemas computacionales emocionales aplicados en entornos terapéuticos para la prevención y tratamiento de la DM. Principalmente, gracias a la combinación de una gestión personalizada de los contenidos hacia el paciente tomando en cuenta la importancia de los procesos afectivos asociados a estas patologías. Este trabajo abre nuevas líneas de investigación, como la aplicación de este sistema en otras patologías de salud mental en las qu[CA] Interactuar es defineix com la realització d'una acció recíproca entre dos o més persones o coses. Particularment en informàtica, el terme interacció es refereix a la disciplina que estudia l'intercanvi d'informació entre les persones i computadores, i es sol conèixer pel terme anglosaxó Human-Computer Interaction (HCI). Un bon disseny i un adequat desenvolupament del software és necessari per aconseguir una HCI eficient que faciliti l'acceptabilitat del sistema per l'usuari. En entorns clínics és fonamental eliminar qualsevol tipus de barrera i facilitar la interacció entre els pacients i el computador. És de vital importància que hi hagi una bona comunicació entre l'usuari (o pacient) i el computador, per aquest motiu el sistema ha d'estar dissenyat pensant en les necessitats actuals, cambiants i personals de l'usuari, basant-se en la metodologia de disseny centrat en l'usuari. El propòsit principal d'aquesta investigació és la identificació de millores en HCI aplicada en entorns clínics, en concret per donar suport a persones amb trastorns mentals com la Depressió Major (DM) i que precisen de teràpies psicològiques adequades i contínues. Gràcies a tècniques d'Intel·ligència Artificial, és possible automatitzar eficientment certes accions asociades al processos de les teràpies cognitiu-conductuals. Els sistemes computacionals de ajuda a la CBT, requereixen d'una adaptabilitat i variabilitat en la interacció per afavorir la usabilitat del sistema i assegurar la continuïtat de la motiviació del pacient. Una bona gestió d'aquesta automatització influiria en l'acceptabilitat dels pacients i podria millorar la seva adherència als tractaments i per tant millorar el seu estat de salut. Addicionalment, la unió de processos deliberatius dinàmics poden alliberar recursos clínics, millorant el control dels pacients, i reduint els temps d'espera i els costos econòmics. En aquest sentit, els esforços d'aquesta Tesi s'han centrat en la investigació de dues línies diferents: (1) la selecció i planificació adequada dels continguts presentats durant la interacció a través d'una planificació dinàmica i personalitzada, i (2) l'adequació de la comunicació dels continguts cap al pacient tenint en compte la importància dels processos afectius associats a aquestes patologies. Els Sistemes Basats en Regles (SBR) han estat la eina utilitzada per donar suport als dos mòduls principals que componen el Framework presentat en aquesta Tesi: el mòdul de gestió dels continguts oferits a l'usuari; i el mòdul emocional. Conclosa la fase de disseny, desenvolupament i testeig, el Framework va ser adaptat als dominis corresponents i integrat en sistemes madurs per ser avaluat en dos escenaris reals, per validar la viabilitat i l'adequació del Framework d'aquesta tesi. Primerament, el sistema es va aplicar durant tres anys en el tractament de la DM major en diversos centres clínics europeus en el context del Projecte Europeu d'investigació Help4Mood. Finalment, el sistema va ser avaluat en la tasca de prevenció de la DM i del suïcidi al Projecte Local d'investigació PrevenDep, d'un any de durada. El feedback de les avaluacions han demostrat que el HCI del Framework obté uns nivells alts d'usabilitat i acceptació, gràcies a la personalització, variabilitat i adaptació dels continguts i de la comunicació. Els experiments computacionals duts a terme en aquesta Tesi han permès avançar l'estat de l'art de sistemes computacionals emocionals aplicats en entorns terapèutics per a la prevenció i tractament de la DM. Principalment, gracies a la combinació d'una gestió personalitzada dels continguts cap al pacient tenint en compte la importància dels processos afectius associats a aquestes patologies. Aquest treball obre noves línies d'investigació, com l'aplicació d'aquest sistema en altres patologies de salut mental en què sigui recomanable l'aplicació de sessions terapèutiques.Bresó Guardado, A. (2016). A Computational Framework for Planning Therapeutical Sessions aimed to Support the Prevention and Treatment of Mental Health Disorders using Emotional Virtual Agents [Tesis doctoral no publicada]. Universitat Politècnica de València. https://doi.org/10.4995/Thesis/10251/64082TESI

SBVR meanings and representations metaschemas

The Semantics of Business Vocabulary and Business Rules (SBVR), v1.0 document (Object Management Group 2008) is an Available Specification, published by the Object Management Group (OMG), that defines the vocabulary and rules for documenting the semantics of business vocabulary, business facts and business rules. The specification is applicable to the domain of business vocabularies and business rules of all kinds of business activities of all kinds of organizations. It is conceptualized optimally for business people rather than automated rules processing, and is designed to be used for business purposes, independent of information system designs. This report describes two metamodels as instances of MOF: the first one is the subset of the SBVR metamodel necessary for describing conceptual schemas as a combination of concepts and facts as defined in SBVR. The second one describes the subset of the SBVR metamodel concerning representations of the meanings.Postprint (published version

Design and Implementation of a Research Data Management System: The CRC/TR32 Project Database (TR32DB)

Research data management (RDM) includes all processes and measures which ensure that research data are well-organised, documented, preserved, stored, backed up, accessible, available, and re-usable. Corresponding RDM systems or repositories form the technical framework to support the collection, accurate documentation, storage, back-up, sharing, and provision of research data, which are created in a specific environment, like a research group or institution. The required measures for the implementation of a RDM system vary according to the discipline or purpose of data (re-)use. In the context of RDM, the documentation of research data is an essential duty. This has to be conducted by accurate, standardized, and interoperable metadata to ensure the interpretability, understandability, shareability, and long-lasting usability of the data. RDM is achieving an increasing importance, as digital information increases. New technologies enable to create more digital data, also automatically. Consequently, the volume of digital data, including big data and small data, will approximately double every two years in size. With regard to e-science, this increase of data was entitled and predicted as the data deluge. Furthermore, the paradigm change in science has led to data intensive science. Particularly scientific data that were financed by public funding are significantly demanded to be archived, documented, provided or even open accessible by different policy makers, funding agencies, journals and other institutions. RDM can prevent the loss of data, otherwise around 80-90 % of the generated research data disappear and are not available for re-use or further studies. This will lead to empty archives or RDM systems. The reasons for this course are well known and are of a technical, socio-cultural, and ethical nature, like missing user participation and data sharing knowledge, as well as lack of time or resources. In addition, the fear of exploitation and missing or limited reward for publishing and sharing data has an important role. This thesis presents an approach in handling research data of the collaborative, multidisciplinary, long-term DFG-funded research project Collaborative Research Centre/Transregio 32 (CRC/TR32) “Patterns in Soil-Vegetation-Atmosphere Systems: Monitoring, Modelling, and Data Assimilation”. In this context, a RDM system, the so-called CRC/TR32 project database (TR32DB), was designed and implemented. The TR32DB considers the demands of the project participants (e.g. heterogeneous data from different disciplines with various file sizes) and the requirements of the DFG, as well as general challenges in RDM. For this purpose, a RDM system was established that comprises a well-described self-designed metadata schema, a file-based data storage, a well-elaborated database of metadata, and a corresponding user-friendly web interface. The whole system is developed in close cooperation with the local Regional Computing Centre of the University of Cologne (RRZK), where it is also hosted. The documentation of the research data with accurate metadata is of key importance. For this purpose, an own specific TR32DB Metadata Schema was designed, consisting of multi-level metadata properties. This is distinguished in general and data type specific (e.g. data, publication, report) properties and is developed according to the project background, demands of the various data types, as well as recent associated metadata standards and principles. Consequently, it is interoperable to recent metadata standards, such as the Dublin Core, the DataCite Metadata Schema, as well as core elements of the ISO19115:2003 Metadata Standard and INSPIRE Directive. Furthermore, the schema supports optional, mandatory, and automatically generated metadata properties, as well as it provides predefined, obligatory and self-established controlled vocabulary lists. The integrated mapping to the DataCite Metadata Schema facilitates the simple application of a Digital Object Identifier (DOI) for a dataset. The file-based data storage is organized in a folder system, corresponding to the structure of the CRC/TR32 and additionally distinguishes between several data types (e.g. data, publication, report). It is embedded in the Andrew File System hosted by the RRZK. The file system is capable to store and backup all data, is highly scalable, supports location independence, and enables easy administration by Access Control Lists. In addition, the relational database management system MySQL stores the metadata according to the previous mentioned TR32DB Metadata Schema as well as further necessary administrative data. A user-friendly web-based graphical user interface enables the access to the TR32DB system. The web-interface provides metadata input, search, and download of data, as well as the visualization of important geodata is handled by an internal WebGIS. This web-interface, as well as the entire RDM system, is self-developed and adjusted to the specific demands. Overall, the TR32DB system is developed according to the needs and requirements of the CRC/TR32 scientists, fits the demands of the DFG, and considers general problems and challenges of RDM as well. With regard to changing demands of the CRC/TR32 and technologic advances, the system is and will be consequently further developed. The established TR32DB approach was already successfully applied to another interdisciplinary research project. Thus, this approach is transferable and generally capable to archive all data, generated by the CRC/TR32, with accurately, interoperable metadata to ensure the re-use of the data, beyond the end of the project

An object-oriented approach to the translation between MOF Metaschemas

Since the 1960s, many formal languages have been developed in order to allow software engineers to specify conceptual models and to design software artifacts. A few of these languages, such as the Unified Modeling Language (UML), have become widely used standards. They employ notations and concepts that are not readily understood by "domain experts," who understand the actual problem domain and are responsible for finding solutions to problems.The Object Management Group (OMG) developed the Semantics of Business Vocabulary and Rules (SBVR) specification as a first step towards providing a language to support the specification of "business vocabularies and rules." The function of SBVR is to capture business concepts and business rules in languages that are close enough to ordinary language, so that business experts can read and write them, and formal enough to capture the intended semantics and present them in a form that is suitable for engineering the automation of the rules.The ultimate goal of business rules approaches is to build software systems directly from vocabularies and rules. One way of reaching this goal, within the context of model-driven architecture (MDA), is to transform SBVR models into UML models. OMG also notes the need for a reverse engineering transformation between UML schemas and SBVR vocabularies and rules in order to validate UML schemas. This thesis proposes an automatic approach to translation between UML schemas and SBVR vocabularies and rules, and vice versa. It consists of the application of a new generic schema translation approach to the particular case of UML and SBVR.The main contribution of the generic approach is the extensive use of object-oriented concepts in the definition of translation mappings, particularly the use of operations (and their refinements) and invariants, both formalized in the Object Constraint Language (OCL). Translation mappings can be used to check that two schemas are translations of each other, and to translate one into the other, in either direction. Translation mappings are declaratively defined by means of preconditions, postconditions and invariants, and they can be implemented in any suitable language. The approach leverages the object-oriented constructs embedded in Meta Object Facility (MOF) metaschemas to achieve the goals of object-oriented software development in the schema translation problem.The generic schema translation approach and its application to UML schemas and SBVR vocabularies and rules is fully implemented in the UML-based Specification Environment (USE) tool and validated by a case study based on the conceptual schema of the Digital Bibliography & Library Project (DBLP) system

Advertising America: The Printing, Publication, and Promotion of English New World Books, 1553-1600

This thesis explores how the paratexts to and physical features of English Tudor books about the New World presented the books’ content to their original readers. The contribution this thesis makes to knowledge is threefold. First, the field of study of English travel and colonial literature lacks a bibliographically informed account of how the books’ constitutive elements of type and paper affect meaning. Widespread use of modern editions of the few accessible texts effaces the originals’ rich aesthetic, structural and tactile forms and fails to comprehensively historicise the production and intentions of the books. The careful, contextualised examinations of typefounts and composition included in this thesis go beyond what has been previously done and suggest agendas for further, necessary and illuminating bibliographical work. Second, the thesis presents the first comprehensively investigative survey of how the paratextual elements of the books marketed the New World to Tudor England. It goes beyond John Parker’s fifty-year-old _Books to Build an Empire_ (1965) by considering the full range of forty-three editions’ paratextual apparatus, not just prefaces, proems and dedications. It is simultaneously a counterbalance to the narrow focus on Richard Hakluyt’s anthological _Principal Navigations_ (1598-1600). The thesis begins the much-needed recovery of the conceptual and publication histories of both the constitutive texts reprinted in _Principal Navigations_ and those not included in Hakluyt’s anthology that are nontheless relevant to the history of the genre. Third, this survey that challenges a still powerful teleology: that the publications were unequivocally books to build an empire. Many of these books were in fact marketed as recreational reads. As the paratextual, structural and material features of many of the books this thesis looks at are under-explored and under-reported, close examination of multiple exemplars was necessary to ensure that this thesis is a representative and reliable record of the marketing strategies used to promote Tudor books about America